Back up VMware virtual machines
Use a backup job that talks to vSphere, writes changed blocks elsewhere, and can register the virtual machine on a recovery host.
Changed-block tracking lets a job copy only what changed since the last run. Enable it on the virtual machines you protect, and check that the backup product still falls back to a full read if tracking resets after a storage vMotion.
Exclude temporary disks and ISO mounts from the job, but include every disk the guest needs to boot. Store the copy on a datastore or object store that is not the production VMFS volume.
Record the vCenter name, the folder, and the network port group the restore will use. A backup that cannot be registered on an isolated host is not finished.